[f. next: cf. prec. and -ATION.] The formation of vacuoles; change to a vacuolar state.
1858. Carpenter, Veg. Phys., § 318. In other cases it would appear that a number of cells are formed by a process of vacuolation.
1881. Mivart, Cat, 329. Vacuolation—denoting the spontaneous resolution of part of a more or less dense structure in such a way as to give rise to a cavity or cavities within it.
1899. Allbutt’s Syst. Med., VI. 508. Vacuolation of the nerve-cell is peculiarly frequent in senile brain atrophy.
