ppl. a. [f. VACUOLE: cf. next.] Rendered vacuolar; modified or altered by vacuolation.
1859. Huxley, Oceanic Hydrozoa, 84. The cavity of the base of the involucrum appears to become filled up by vacuolated tissue.
1878. F. J. Bell, trans. Gegenbauer’s Comp. Anat., 24. There are often vacuolated spaces in the cells, which are filled with a fluid.
1896. Allbutt’s Syst. Med., I. 211. Cell invaginations, the protoplasm of which is highly vacuolated.
