[f. as next, or a. F. vaccine (1800), cow-pox, vaccination, vaccin (1812), vaccine matter, = It. and Pg. vaccina, Sp. vacuna.]
† 1. Vaccination. Obs.–1
1803. trans. P. Le Brun’s Mons. Botte, III. 110. Is it to them the world owes inoculation, which they so long opposed; or the vaccine, which they still oppose?
2. Vaccine matter used in vaccination.
1846. [see VACCINATION 1].
1851. Leadam, Homœopathy, 361. A child … totally insusceptible of the influence of vaccine.
1864. Spectator, 375. As ordinary Englishmen say, the vaccine took.
1878. T. Bryant, Pract. Surg., I. 94. It would be also well, for the purpose of keeping up a good supply of vaccine, occasionally to vaccinate direct from the heifer.
fig. 1861. Gen. P. Thompson, Audi Alt., cliv. III. 155. Impressing the advantages of industry, with the chance of acting as a vaccine to the habits of thieves.
attrib. 1889. Buck’s Ref. Handbk. Med. Sci., VII. 518. Ume’s vaccine-scarificator consists of four blades fixed upon a horizontal axis.
b. A preparation of some virus used for the purpose of inoculation.
1894. Daily News, 15 Jan., 3/1. Graduated solutions of what for want of a better word may be called the vaccine.
