[ad. L. vaccīn-us (f. vacca cow), esp. in variolæ vaccinæ cow-pox (Dr. Jenner, 1798). Cf. It. vaccino.]
1. Vaccine disease, pock, = COW-POX.
1799. Med. Jrnl., I. 281. The certainty that the having suffered the vaccine disease, will prove a preservative from the infection of the small-pox. Ibid. (1802), VIII. 169. I found the Vaccine-pock so safe and mild a disease … that I became a convert.
1851. Leadam, Homœopathy, 360. When the system has been satisfactorily infected by the vaccine disease.
b. Appearing in, characteristic of, the disease of cow-pox.
1800. Med. Jrnl., V. 28. Matter taken from a vaccine pustule.
1816. Southey, in Q. Rev., XVI. 383. It might be supposed that, like the vaccine infection, it secured the system against a stronger poison.
1845. Encycl. Metrop., VII. 755/1. The vaccine cicatrix is round, deep, radiated, and puckered.
1888. Encycl. Brit., XXIV. 26/2. Ulceration of the vaccine vesicle … is one of the commoner forms of ‘bad arm.’
2. Vaccine lymph, matter, virus, the characteristic virus of cow-pox (obtained directly or from human subjects) which is employed in vaccination.
1799. Med. Jrnl., II. 25. Manifestly arising from absorption of vaccine matter into the system.
1799. Jenner, Further Obs. Var. Vaccinæ (Crookshank, 1889), II. 188. Mr. Henry Jenner … inserted the vaccine virus into the arm of a child.
1813. D. Milne, in Home Papers (Hist. MSS. Comm.), 159. I gave his phial of vaccine matter to a Dr. Staunton.
1880. A. Flint’s Princ. Med., 1043. The vesicles … contain a transparent, viscid liquid called the vaccine lymph.
1897. Allbutt’s Syst. Med., II. 644. Essential constituents of vaccine lymph.
3. Vaccine inoculation, = VACCINATION 1.
1799. Med. Jrnl., II. 310. Extracts of Letters on the Vaccine Inoculation.
1802. Ann. Reg., Hist. Europe, 182/2. Dr. Jenner, the discoverer of the vaccine inoculation.
1806. R. Willan (title), On Vaccine Inoculation.
b. Connected with vaccination.
1812. Examiner, 21 Sept., 597/2. The National Vaccine Establishment has … published its report.
1816. J. Ring (title), A caution against vaccine swindlers and impostors.
4. Derived from, pertaining or relating to, cows.
1804. Med. Jrnl., XII. 242. We have milk…, butter,… cheese. All this is vaccine matter.
1864. Daily Tel., 10 June. Cows … executed a kind of comic vaccine war dance.
1881. S. R. Macphail, Relig. House of Pluscardyn, ii. 51. When any animal about the farm became ill, there was generally to be found some skilled person who professed vaccine medical knowledge.
