See quotation.
1781. It is from the singing of the tree-frog, that the Americans have acquired the name of Little Isaac.Samuel Peters, History of Connecticut, p. 262 (Lond.). (Italics in the original.) [See also TREE-FROG, 1781.]
1837. What a cunning little Isaac of a brother this is.Balt. Comml. Transcript, Aug. 16, p. 2/2: from the Richmond Compiler.