Now rare. [ad. L. tōph-us, more correctly tōf-us: see TOPHUS.]

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  1.  Usually toph stone: Travertin, or other soft stone: = TOPHUS 1.

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a. 1552.  Leland, Itin., VI. 72. A Quarre of Tophe Stone by Driselege, wherof much of the Castelle was buildid.

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1577.  Harrison, England, III. xv. (1878), II. 61. For Tophe stone, not a few allow of the quarrie that is at Drisley, diuerse mislike not of the veine of hard stone that is at Oxford, and Burford.

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1811.  J. Milner, Eccles. Archit. Eng. Mid. Ages, 95. Arched with hard stone for the ribs and light toph stone for the interstices.

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  2.  Path. A calcareous deposit or calculus formed within the human or animal body: = TOPHUS 2.

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1584.  T. Bastard, Chrestoleros (1880), 10. Phisition Mirus talkes of saliuation, Of Tophes and Pustules, and Febrication.

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1651.  Biggs, New Disp., § 141. A neutrall nature of a tophe, between a Cartilage and a Stone.

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1694.  Salmon, Bate’s Dispens. (1713), 64/2. It softens, dissipates, yea, and dissolves the chalky Concretions … pocky Nodes, Tophs, Gums, and Swellings. Ibid., 682/1. It cleanses the Skin,… takes away Gouty Tophs, cures the Leprosie.

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1706.  Phillips (ed. Kersey), Toph, a word us’d by some Chirurgical Writers for a kind of Swelling in the Bones.

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1822–7.  Good, Study Med. (1829), IV. 532. Some structural irritation within the cavity of the skull, such as a node or toph.

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1843.  R. J. Graves, Syst. Clin. Med., xxviii. 355. Exanthemata … nodes, tophes, syphilitic gout and rheumatism.

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