[ad. L. stimulātiōnem, n. of action f. stimulāre to STIMULATE. Cf. F. stimulation (14–15th c. in Hatz.-Darm.), Sp. estimulacion, Pg. estimulação, It. stimolazione.] The action of stimulating or condition of being stimulated.

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  1.  A pricking, goading or spurring on to action; incitement; † pricking or compunction of conscience (obs.).

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1526.  Pilgr. Perf. (W. de W., 1531), 263. Ye stimulacyons of the flesshe.

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1640.  Ld. Digby, Sp., in Rushw., Hist. Coll., III. (1692), I. 171. The Danger, when either true, or pretended Stimulation of Conscience hath once given a multitude Agitation.

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1751.  Johnson, Rambler, No. 145, ¶ 5. That industry which the stimulations of necessity … enforce.

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1860.  Mill, Repr. Govt. (1865), 27/2. To supply reasons to his understanding, and stimulation to his feeling.

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1873.  E. H. Clarke, Sex in Educ., 106. The same girls are apt to be quick,… and need not stimulation, but repression.

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  2.  Phys. and Med. The action of a stimulus. a. Excitation to increased activity, quickening of some vital function or process (cf. STIMULUS 1). In quot. 1733 loosely, stimulating property (cf. STIMULUS 1 b). b. Excitation of an organ or tissue to its specific activity (cf. STIMULUS 3).

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1733.  Cheyne, Eng. Malady, II. vii. § 2 (1734), 186. The Bile, by its natural Acrimony and Stimulation [etc.].

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1799.  Med. Jrnl., II. 217. The vaccine poison … produces inflammation, a little tumour, and sometimes pustule, which are not the effects of the specific stimulation of the matter.

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1834.  J. Forbes, Laennec’s Dis. Chest (ed. 4), 373. The stimulation communicated to or subtracted from the brain by the light.

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1843.  R. J. Graves, Syst. Clin. Med., xv. 183. We should resort to stimulation by wine.

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1879.  Carpenter, Ment. Phys., App. 719. Muscles … can be thrown into contraction by stimulation of these lower centres.

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1899.  W. S. Hall, Text-bk. Physiol., 52. A muscle-cell responds to all stimuli by contracting, a gland-cell by secreting, while the stimulation of the optic nerve can only produce the sensation of light.

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