An enlargement of the spleen or liver caused by ague.
1641. Milton, Ch. Discip., II. (1851), 42. A mere ague-cake coagulated of a certaine Fever they have, presaging their time to be but short.
1801. E. Darwin, Zoon., II. 47. The liver, spleen, or pancreas; one or more of which are frequently so enlarged in the autumnal intermittents as to be perceptible to the touch externally, and are called by the vulgar ague-cakes.
